Anatomic left lateral sectionectomy consists of the removal of the left lateral segments II and III of the liver, which represent about 25% of the liver volume. The left lateral segment has its individual portal and arterial supply, while its biliary anatomy is not uniform. Usually the segmental bile ducts converge into a single duct and the latter join with the left median duct and the caudate branch into the left hepatic duct. Arterial blood supply entirely comes from a branch of the left hepatic artery, while portal venous anatomy frequently shows variations. The line of resection follows the falciform ligament until the left hepatic vein has been reached.